We invest in visionary science start-ups.

Industrial buildings and data centers define competitiveness, resilience, and energy demand. Yet their early stage planning remains fragmented and constrained, even as complexity continues to rise. factorymaker transforms this decisive phase into a computational process. By enabling systematic exploration and optimisation of design alternatives, the platform allows efficiency, flexibility, and sustainability to be embedded from the start. We believe factorymaker is building a foundational layer for how complex industrial systems will be conceived and realised in the future.

Amplifold elevates rapid diagnostics to a new performance level. By integrating DNA origami nanostructures into conventional lateral flow tests, the company increases sensitivity by up to one hundred fold without requiring instruments or changes to manufacturing. This enables laboratory-level performance in a familiar strip-based format, opening new possibilities in infectious disease, oncology and decentralised testing.

Autonomous cars are among the most complex physical AI systems ever built. They must operate safely in open, dynamic environments, yet validating them in the real world remains slow, expensive, and fundamentally limited.
AVES Reality addresses this bottleneck by building a foundational infrastructure layer for autonomous driving: accurate, simulation-ready 3D digital twins of the real world, generated automatically at global scale.
Using satellite and aerial imagery combined with geospatial AI, advanced computer graphics, and physics-aware modeling, AVES Reality reconstructs cities, road networks, and intersections as deterministic digital environments. These are not visual replicas, but procedurally generated worlds enriched with physical and semantic information that autonomous systems can reliably learn from, train in, and be validated against.

Ora Computing is an AI deployment company specializing in optimizing and compressing Artificial Intelligence (AI) foundation models. They develop AI techniques that automate manual labor mostly on edge devices, such that small and performant models can be deployed on phones, laptops, IoT devices, and cars.

Syntropic develops a non-invasive and non-pharmaceutical treatment for mental health disorders. Through light stimulation, neural remodeling is activated by instructing the immune cells of the brain to support in healing and recovery.

ONCO-Boost, the first product from HEPHAISTOS-Pharma’s platform, is a natural TLR4 agonist that stimulates the patients’ own immune system to strengthen both innate and adaptive immune systems to strengthen their responses against cold tumors.

Batteries are needed to store renewable energy – it's not always windy when you want it to be, and the same applies to the hours of sunshine. Rivus’ idea is for gigantic batteries to be placed at solar and wind farms.

Infrared.city is a platform for intelligent and resilient architecture and construction design powered by Artificial Intelligence. Using simulation prediction models, infrared.city can deliver simulation results at a fraction of the computational time and financial cost. Their state of the art machine learning models provide real-time feedback on the performance of design proposals and can guide climate informed decisions at every step of the process.

subdron is dedicated to transforming underwater inspections through the development of close range navigation for Autonomous Underwater Vehicles (AUVs) and automatized data processing and analysis. By leveraging vanguard hardware technology and artificial intelligence, subdron aims to revolutionize the way underwater structures such as port infrastructure and ship hulls are inspected for damages and biofouling. Their mission is to provide efficient, cost-effective, and environmentally friendly solutions for underwater infrastructure management.

ReCatalyst reduces required platinum in fuel cell catalysts for applications in heavy duty transport, while improving efficiency and durability

VitreaLab is commercializing integrated laser powered photonic devices that will transform displays as we know them. Inspired by quantum photonic technologies, VitreaLab developed its “Quantum Light Engine” which is a light source capable of illuminating AR, VR, and 3D displays with laser light of unprecedented brightness and perfect colour quality while consuming just a fraction of the energy needed by other technologies.

Solgate’s founders combine deep expertise in the biology of solute carriers with unique chemistry-based approaches for accelerated drugging of difficult targets. Current projects are focused on CNS and immunology indications.

Sarcura set out to tackle one of the toughest challenges in advanced medicine: how to manufacture cell therapies at scale. With an interdisciplinary founders team and a research-derived, innovative product for a growing market, they aimed to miniaturize and automate cell therapy production on a chip.

At xista science ventures, we are proud to have supported this journey from its early days, providing capital, infrastructure, and a place in our community. While Sarcura will not continue as a company, it's achievements and people remain part of our ecosystem as a Retired Innovation Pioneer. This is the reality of science-driven entrepreneurship: not every venture reaches the market, but each one advances the frontier for those who follow.

Ribbon Biolabs is a synthetic biology leader driving DNA synthesis beyond the limits of current technologies. With their automated, enzyme-based platform, Ribbon Biolabs can provide synthetic DNA molecules without size or sequence limitations at a high level of accuracy and at unprecedented speed.

Transparency and actionable insights are becoming increasingly important in an interconnected world with complex supply chains and increasing disruption risks. Finding, monitoring and analyzing disruption- and sustainability risks is a tremendous challenge for almost every industry. With its technology, prewave is making supply chains more resilient and sustainable.

Sustainable energy systems need ambitious goals, novel technologies, as well as stringent execution. nista develops an AI-powered data analysis software that they offer as an Energy Efficiency as a Service tool for the energy intensive industry.

G.ST Antivirals is a clinical-stage biotech company that develops broad-spectrum antivirals against respiratory tract infections. Founded in 2019 by Guido Gualdoni and Johannes Stöckl, the company leverages an innovative host cell-based strategy to overcome respiratory viral infections. This approach is based on a high-impact paper on the interaction of a respiratory virus with the infected cell, which was published by the founders while working at the Medical University of Vienna.

The immune system protects our body against bacteria, viruses and other external threats to our health. Dendritic cells (DCs) play a central role by recognizing such pathogens, processing them and training other immune cells to act against them. At the same time, DCs are also responsible for tolerating the body’s own structures (autoantigens). This complex interaction is achieved by an „orchestra“ of different types of DCs. Cutanos aims to use these mechanisms to develop both vaccines and therapies against autoimmune diseases and allergies.

The cell is at the center of current and future biological science. Future trends require novel technologies to unlock their full potential. The combination of electrodynamics and biotechnology perfectly complements the requirements of emerging industries when it comes to efficient analysis and modulation of biological cells.

Brightmind.AI is developing therapeutic TMS (transcranial magnetic stimulation) devices for home use, with a first indication of migraine.

By means of synthetic biology and genetic code expansion Valanx has developed a novel site-specific protein conjugation platform that allows precise control over conjugation site and number of conjugations on the protein of interest. Based on this platform Valanx is developing a number of cutting-edge biologics towards potential treatments for various indications.

Artificial Intelligence (AI) is increasingly prevalent in business and society. An area where AI is performing well already is healthcare, with significant developments in early detection, diagnostics, decision making or workflow support providing clinical value.

Neurolentech is a spinoff of ISTA (Institute of Science and Technology Austria) focused on personalized medicine for neurodevelopmental disorders. The company is developing and characterizing libraries of patient-derived neuronal cells, and will leverage this unique resource for the development of novel therapeutics to tackle severe forms of autism and epilepsy.

Brainhero is a medtech company that is focused on unlocking and enhancing the potential of children with autism spectrum disorder (ASD) or attention-deficit/hyperactivity disorder (ADHD). Their CE-certified neurofeedback therapy system, a Class IIa medical device (MDR), includes a wearable EEG device and user-friendly software, providing flexibility for their target audience.

Additionally, Brainhero is developing EEG technology for home-based diagnostic measures to detect neurological issues early. With a long-term vision, Brainhero aims to address a broader range of neurological impairments, responding to the increasing global mental health challenges.